Endocrine Abstracts

Background: Poor adherence with thyroxine treatment is a common problem faced by endocrinologists the world over. Abnormally elevated TSH levels, with rising levels of treatment is an ongoing management challenge, especially with patient insistence of compliance. There are a number of investigative tools advocated. We present a case managed through an observed thyroxine absorption test.Methods: A 36-year-old woman was referred by her primary care practit...

Objective: To study O6-methylguanine-DNA methyltransferase (MGMT) immunoexpression to access the efficacy of Temozolamide (TMZ) as a part of multimodality treatment.Background: Aggressive or residual pituitary tumours are associated with substantial morbidity. Treatment options are often limited, and chemotherapy are associated with dismal results. Recent reports have documented the efficacy of TMZ therapy in aggressive pituitary tumors resistant to mult...